Chronic obstructive pulmonary disease (COPD) is a chronic, progressive lung disorder characterized by persistent airflow limitation that is not fully reversible. It develops gradually, most often due to long term exposure to harmful Chronic obstructive pulmonary disease: Risks, symptoms and prevention Mayo Clinic News Network Electronic cigarette use and its association with asthma, chronic obstructive pulmonary disease (COPD) and asthma COPD overlap syndrome among never cigarette smokers Pictures of COPD's Effect on the Lungs Elevated risk of developing COPD with e cigarette use: Study