How the glutathione cycle shapes synaptic glutamate activity Increasing glutathione levels by a novel posttranslational mechanism inhibits neuronal hyperexcitability ScienceDirect Brain health depends on balance. From energy production to antioxidant protection and immune regulation, multiple systems work together to support how the brain functions. Glutathione plays a central role in maintaining Research Communities by Springer Nature In Vivo Brain GSH: MRS Methods and Clinical Applications