Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Have a brown black spot on your lips??, Labial Melanotic Macules, not cancerous , #drrubanskinguru , #dermatologist, #sunspots Are Freckles on Lips a Cause for Concern? Causes, Remedies Pigmented Lesions of the Oral Mucosa Pocket Dentistry