Figure 1 from Oral melanotic macule a case report. Semantic Scholar Oral melanotic macules are harmless but can be removed easily with laser treatment! Quick, safe, and effective. Say hello to even toned lips! #laser #candela #pico #lips #face #makeup #spa What Caused These Multiple Hyperpigmented Macules of the Mouth? Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Oral Melanotic Macule MEDizzy