Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Does anyone know what this black mark on my lip is? Started last August so it's I've had it nearly a year, was living in Spain at the time for 6 months Oral Melanotic Macule MEDizzy Congenital Melanotic Macule of the Tongue: A Five Year Follow up Dermatology Practical & Conceptual