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Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Alzheimer's Drug Donanemab Helps Most When Taken Early in Disease Scientific American Surprise: HDAC Goes Down, Not Up, in Alzheimer's Disease ALZFORUM Dihexa Capsules Premium Cognitive Support by Annular Annular Premium Health Formulas Neuronal hyperexcitability in Alzheimer's disease: what are the drivers behind this aberrant phenotype? Translational Psychiatry
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