Cagrilintide used for the treatment of obesity and type 2 diabetes Combined cagrilintide and semaglutide for weight management well tolerated in early clinical trials 2 Minute Medicine Cagrilintide & Semaglutide peptides Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 24 mg for weight management: a randomised, controlled, phase 1b trial The Lancet