An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic The labial melanotic macule: a review of 79 cases Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Oral pigmented lesions: a pragmatic approach to diagnosis and management Faculty Dental Journal COM Jan. 2008 Diagnosis UW School of Dentistry