Paracetamol toxicity Deranged Physiology NAPQI an overview ScienceDirect Topics Alcohol and paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting, Haggling with HAGMA: A Common Medication with an Uncommon Differential Renal Fellow Network What Are the Potential Sites of Protein Arylation by N Acetyl p benzoquinone Imine (NAPQI)? Chemical Research in Toxicology