Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after Pigmented (Purple or Brown) Lesions in the Mouth Pigmented (Purple or Brown) Lesions in the Mouth Kazemi Oral Surgery Facialart.com Pigmented Lesions of the Oral Cavity Pocket Dentistry Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a Pigmented Lesions of the Oral Mucosa Springer Nature Link