What Caused These Multiple Hyperpigmented Macules of the Mouth? Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in PPT Oral Pigmentation PowerPoint Presentation, free download ID:9729452 Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) La Bouche Parfaite Pigmented Lesions of the Oral Mucosa Springer Nature Link
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melanotic macule causes Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome